Our Research


Brownstien M, Lazar M, Botvinnik A, Shevakh C, Blakolmer K, Lerer L, Lifschytz T, Lerer B.   Striking Long-Term Beneficial Effects of Single Dose Psilocybin and Psychedelic Mushroom Extract in the SAPAP3 Rodent Model of OCD-Like Excessive Self-Grooming. Molecular Psychiatry (Immediate Communication) 2024 Oct 11. doi: 10.1038/s41380-024-02786-0. Online ahead of print.

 

Lerer E, Botvinnik A, Shahar O, Grad M, Blakolmer K, Shomron N, Lotan A, Lerer B, Lifschytz T.  Effects of psilocybin, psychedelic mushroom extract and 5-hydroxytryptophan on brain immediate early gene expression: Interaction with serotonergic receptor modulatorsFrontiers in Pharmacology 2024 Apr 18;15:1391412. doi: 10.3389/fphar.2024.1391412

Shahar O, Botvinnik A, Shwartz A, Lerer E, Golding P, Buko A, Hamid E, Kahn D, Guralnick M, Blakolmer K, Wolf G, Lotan A, Lerer L, Lerer B, Lifschytz T. Effect of chemically synthesized psilocybin and psychedelic mushroom extract on molecular and metabolic profiles in mouse brain. Molecular Psychiatry. 2024 Feb 20. doi: 10.1038/s41380-024-02477-w. Online ahead of print. PMID: 38378926

Heresco-Levy U, Lerer B. Synergistic psychedelic – NMDAR modulator treatment for neuropsychiatric disorders. Molecular Psychiatry. 2023 Nov 9. doi: 10.1038/s41380-023-02312-8. Online ahead of print. PMID: 37945694

Singh S, Botvinnik A, Shahar O, Wolf G, Yakobi C, Saban M, Salama A, Lotan A, Lerer B, Lifschytz T. Effect of psilocybin on marble burying in ICR mice: role of 5-HT1A receptors and implications for the treatment of obsessive-compulsive disorder. Translational Psychiatry. 2023 May 10;13(1):164. doi: 10.1038/s41398-023-02456-9. PMID: 37164956

Lerer L, Reynolds E, Varia J, Blakolmer K, Lerer B. Incilius alvarius Cell-Based Synthesis of 5-Methoxy-N,N-Dimethyltryptamine. Psychedelic Medicine. Mar 2023.38-42.http://doi.org/10.1089/psymed.2022.0001

Wolf G, Singh S, Blakolmer K, Lerer L, Lifschytz T, Heresco-Levy U, Lotan A, Lerer B. Could psychedelic drugs have a role in the treatment of schizophrenia? Rationale and strategy for safe implementation. Molecular Psychiatry. 2023 Jan;28(1):44-58. doi: 10.1038/s41380-022-01832-z. Epub 2022 Oct 24. PMID: 36280752

Matzopoulos R, Morlock R, Morlock A, Lerer B, Lerer L. Psychedelic Mushrooms in the USA: Knowledge, Patterns of Use, and Association With Health Outcomes. Frontiers in Psychiatry. 2022 Jan 3;12:780696. doi: 10.3389/fpsyt.2021.780696. eCollection 2021. PMID: 35046855

Shahar O, Botvinnik A, Esh-Zuntz N, Brownstien M, Wolf R, Lotan A, Wolf G, Lerer B, Lifschytz T. Role of 5-HT2A, 5-HT2C, 5-HT1A and TAAR1 Receptors in the Head Twitch Response Induced by 5-Hydroxytryptophan and Psilocybin: Translational Implications. International Journal of Molecular Science. 2022 Nov 16;23(22):14148. doi: 10.3390/ijms232214148. PMID: 36430623